STUDY - Technical - New Dacian's Medicine
How
it Works... Our "Body" (1).
Translation Draft
As you could "see" in previous posts, a cell that does not exchange with the outside does not work (literally), which will attract, in a shorter or longer time, the cessation of the existence of that cell. In the case of cell groups, things change to some extent because "communication" occurs between them, even when there are no "exchanges" with the outside (and the cessation of the existence of that group is slower, supported a kind of delay in the cancellation of the group through various mechanisms).
Returning to a single cell, if we place it in a beneficial environment, it makes the exchanges it is capable of, in optimal parameters. If we place it in a non-beneficial (even harmful) environment, the cell will become ill (in the concrete sense of the sick term), the end of the existence of the cell being slower, it "fighting" through various coping mechanisms (which attract the state of "sick") as much as possible, until its existence ends. Replacing the cell in the beneficial environment (before its existence ceases), it "extracts" (through exchanges with that environment) everything it needs to return to optimal functioning (health status).
A group of cells placed in a beneficial environment behaves similar to a small "particularity"... They work together to promote the optimal functioning of the whole group. Here comes a new "particularity". Under the conditions of a beneficial environment that provides everything that is needed everything is OK without any other effects. But if this beneficial environment is not able to provide the whole group of cells with everything that is needed, they proceed to a kind of resource allocation according to the available, the whole group adapting to the "existing" resource. Yes, you read well, the cells do not know the manifestations of selfishness and thus preferential allocation of resources.
All experiments confirm this behavior. Explanations?!? Some researchers point out that any group of cells has a common source of development, in the sense that they all originate from a "first cell" from which the division has been reached to that group, and thus the whole group is the "extension" of that first cell that acts uniformly even in the case of the group formed by "subsequent" divisions. Moreover, the existence of communication that is carried out either by chemical markers or by electromagnetic waves given by the membrane potential (and not only) determines a kind of "group automatism" in the sense of the optimal functioning of the whole group. Interesting, isn't it? And if we place this group of cells in a non-beneficial environment, the entire group of cells will "place" in the "sick" status by adapting to the maximum possible possibility that the entire group will benefit from the existing resources.
And if that environment attracts cell death, the rest of the "more resistant" cells will not divide the resources that arise from the disappearance of each dying cell (although it is quite logical this reaction because the lack of a resource is generalized, that resource having no way to exist in the cell that died). It should be pointed out here that there are also cells that devour other cells but, in this case, such cells will never form a group of cells, being only a cluster of "carnivorous" cells (either "cannibals"). So there can be no discussion here about such cells (they will never form an organism, being themselves an individual "organism" that will always remain at the individual cell stage).
There's a little "statement" to insert here, of course inferred from the experiments. All readers of this blog think they know what a stem cell is. Hmmm, I'd better introduce some elements about this stem cell. These cells appear (initially) in the early stages of embryonic development in the cell resulting from fertilization, which is called the egg or zygot cell (in humans, this moment is represented by the "meeting" between the egg and the sperm).
Since I've "started" with the human description, I'm going to present this process at the human "level." After exactly 5 days (after fertilization), the cell division will "produce" exactly 32 cells crammed into the space of the initial membrane of the egg (a formation called blastocyte). Now, the cells arranged on the outside will give rise to the placenta and other auxiliary "support" tissues. It is the moment when the embryo self-implantes into the uterine wall and pregnancy begins. At this point, a disk-shaped cell formation will be "structured", beginning cell development through repeated divisions. On the 14th day of development appears the so-called "primitive line" (primitive streak).
This "line" is a structure that is formed in the early stages of embryo development, and is also a very important concept in bioethics, with some experts arguing that experimentation with human embryos should be allowed only before reaching this stage of development (which is the beginning of the individual development of the embryo, thus, in their conception, the signal of the potential for the emergence of a new and unique human being , an individual entity). Moreover, this "line" represents the boundary of the demarcation (I should have called it the "demarcation line") of the bilateral symmetry that will characterize the fetus. yes, from here on out, you can see from day to day how the new "little man" develops.
We are initially only interested in the stage from fertilization to the appearance of the primitive line. Three germination layers may be delineated during this "range"; endoderm, mesoderm and ectoderm. They are formed with the development of the embryo and from them derive all organs (the entire future organism), each cell and each organ of the body can be classified according to these germ layers. Cells or organs that evolve from the inner germination layer (endoderm) will have the "relay" (command center) in the brain stem, the oldest brain structure.
In the middle germination layer, mesoderm, two groups are distinguished, one "older" and one "newer". Cells and organs that evolved from the "old" mesoderm have the relay in the cerebellum, belonging to the archaic brain, and those that evolved from the "new" mesoderm have the command relay in the brain marrow (the white substance of the brain). Cells and organs that have evolved from the outer germination layer (ectoderm) have the relay in the cerebral cortex (brain bark) that represents the newest (young) formation of our brain.
The first "moment" we can discuss stem cells has just been described. At the moment there are no cells that will become anything specific but, just cell layers composed of non-specialized cells, also called layers of stem cells. Moreover, these stem cells appear permanently, throughout the development range of the human embryo, because they are non-specialized cells that multiply, of course, through cell division and that permanently build the human embryo until the final phase of the fetus and child. As evidence in this permanent "construction" of the human embryo stem lies the way of sampling these stem cells.
They are taken, for example, from the umbilical cord (from here two types of stem cells are harvested: hematopoietic stem cells, harvested from umbilical cord blood and mesenchymal stem cells, harvested from the umbilical cord wall, i.e. from Wharton gelatin), the time of collection (the smaller the embryo, the better) being able to "stretch" throughout the pregnancy period and after (with reference to the actual time of birth). And, while i.e. this time of harvest, stem cells taken in the youngest stages of the embryo (fetus), also called embryonic stem cells, can give rise to any type of cell/tissue (which is why they are called "omnipotent") and are obtained from embryonic tissue (their use is "struck" by the ethical considerations of the medical world, and not only), and adult stem cells (which are harvested in the advanced stages of foetal development) have a slightly more limited ability to differentiate (being called pluripotent or multipotent) and can give rise to cells that can form different tissues (hepatic tissue, blood cells, nervous tissue, bone tissue, muscle, etc.). In current medical "technologies", these stem cells are used in regenerative medicine (but also in the treatment of a large number of conditions).
It would be good if I could give some details about how these stem cells are harvested. Invasive methods I do not want to discuss here because they refer either to an invasive sampling of the embryo itself (which is done either in violation of human, medical, etc. ethics with the slaughter, in most cases of the embryo, or with the justification of the non-viability of the pregnancy or the "necessary abortion" which entails, of course, the "justified" slaughter of the embryo). Well, that's not good, but it's practiced!!! The only non-invasive method of stem cell collection is achieved by means of blood remaining in the umbilical cord (this is a variable volume of blood that remains on the umbilical cord path to the placenta and inside the placenta itself which is richly vascularized) at the time of birth (without forgetting the Wharton gelatin present in both the umbilical cord and the placenta).
And now it's... These stem cells are "preserved" by various methods and then, at the appropriate time, given various "assignments". It comes "now it is now"... Experiments with embryonic stem cells (omnipotent) have confirmed that the placement of these cells in a certain environment "induces" the development of cells, for example, the liver. If the environment in which these cells are introduced changes, they will "produce" muscle cells. Another environment determines the development of nerve cells... And so on, it can "induce" the development of any type of cell. So, remember, it's the environment that determines what the omnipotent stem cells will become. In the case of other stem cells (pluripotents)... Hmmm, things are getting complicated.
For stem cells taken from embryos slaughtered by abortion or other "incidents" of similar value, the embryonic "origin" of the tissue from which they were taken becomes important, with adult stem cells already having "taken" information about the environment on which they will "dedicate" their existence. And thus, they will develop only certain groups of cells that "can" be "initiated" from their embryonic origin. More specifically, the environment will only attract a change of specialization in their development without reaching the stage of omnipotence.
And if you've got a hold of these stem cells non-invasively, there's a problem with the origin of those cells. The cord or placenta blood obviously belongs to the mother and not to the fetus. Or, by extension, it's a common blood. Without wanting to come to the conclusions of several researchers that we humans (actually any body-type life form) constantly generate stem cells that specialize immediately after the moment of their "creation", depending on the environment (as we have "seen" previously, the environment is the main determinant of the result of the "transformation" of the stem cell) and, in certain circumstances, according to the origin of the original embryonic "layer" of that cell.
Therefore, continuing the "logical presentation" of the cell groups, it is obvious that we conclude that the regeneration processes are not carried out simply by dividing a cell into two cells, one of which will take the place of the cell that has disappeared but, in fact, it is an "initial genetic manifestation" in which a cell divides according to its "genetic base" forming an adult stem cell which, "sensing" the environment in which it is located, will become "what it needs to be Interesting or not?!?
I'll continue in future posts!
As you could "see" in previous posts, a cell that does not exchange with the outside does not work (literally), which will attract, in a shorter or longer time, the cessation of the existence of that cell. In the case of cell groups, things change to some extent because "communication" occurs between them, even when there are no "exchanges" with the outside (and the cessation of the existence of that group is slower, supported a kind of delay in the cancellation of the group through various mechanisms).
Returning to a single cell, if we place it in a beneficial environment, it makes the exchanges it is capable of, in optimal parameters. If we place it in a non-beneficial (even harmful) environment, the cell will become ill (in the concrete sense of the sick term), the end of the existence of the cell being slower, it "fighting" through various coping mechanisms (which attract the state of "sick") as much as possible, until its existence ends. Replacing the cell in the beneficial environment (before its existence ceases), it "extracts" (through exchanges with that environment) everything it needs to return to optimal functioning (health status).
A group of cells placed in a beneficial environment behaves similar to a small "particularity"... They work together to promote the optimal functioning of the whole group. Here comes a new "particularity". Under the conditions of a beneficial environment that provides everything that is needed everything is OK without any other effects. But if this beneficial environment is not able to provide the whole group of cells with everything that is needed, they proceed to a kind of resource allocation according to the available, the whole group adapting to the "existing" resource. Yes, you read well, the cells do not know the manifestations of selfishness and thus preferential allocation of resources.
All experiments confirm this behavior. Explanations?!? Some researchers point out that any group of cells has a common source of development, in the sense that they all originate from a "first cell" from which the division has been reached to that group, and thus the whole group is the "extension" of that first cell that acts uniformly even in the case of the group formed by "subsequent" divisions. Moreover, the existence of communication that is carried out either by chemical markers or by electromagnetic waves given by the membrane potential (and not only) determines a kind of "group automatism" in the sense of the optimal functioning of the whole group. Interesting, isn't it? And if we place this group of cells in a non-beneficial environment, the entire group of cells will "place" in the "sick" status by adapting to the maximum possible possibility that the entire group will benefit from the existing resources.
And if that environment attracts cell death, the rest of the "more resistant" cells will not divide the resources that arise from the disappearance of each dying cell (although it is quite logical this reaction because the lack of a resource is generalized, that resource having no way to exist in the cell that died). It should be pointed out here that there are also cells that devour other cells but, in this case, such cells will never form a group of cells, being only a cluster of "carnivorous" cells (either "cannibals"). So there can be no discussion here about such cells (they will never form an organism, being themselves an individual "organism" that will always remain at the individual cell stage).
There's a little "statement" to insert here, of course inferred from the experiments. All readers of this blog think they know what a stem cell is. Hmmm, I'd better introduce some elements about this stem cell. These cells appear (initially) in the early stages of embryonic development in the cell resulting from fertilization, which is called the egg or zygot cell (in humans, this moment is represented by the "meeting" between the egg and the sperm).
Since I've "started" with the human description, I'm going to present this process at the human "level." After exactly 5 days (after fertilization), the cell division will "produce" exactly 32 cells crammed into the space of the initial membrane of the egg (a formation called blastocyte). Now, the cells arranged on the outside will give rise to the placenta and other auxiliary "support" tissues. It is the moment when the embryo self-implantes into the uterine wall and pregnancy begins. At this point, a disk-shaped cell formation will be "structured", beginning cell development through repeated divisions. On the 14th day of development appears the so-called "primitive line" (primitive streak).
This "line" is a structure that is formed in the early stages of embryo development, and is also a very important concept in bioethics, with some experts arguing that experimentation with human embryos should be allowed only before reaching this stage of development (which is the beginning of the individual development of the embryo, thus, in their conception, the signal of the potential for the emergence of a new and unique human being , an individual entity). Moreover, this "line" represents the boundary of the demarcation (I should have called it the "demarcation line") of the bilateral symmetry that will characterize the fetus. yes, from here on out, you can see from day to day how the new "little man" develops.
We are initially only interested in the stage from fertilization to the appearance of the primitive line. Three germination layers may be delineated during this "range"; endoderm, mesoderm and ectoderm. They are formed with the development of the embryo and from them derive all organs (the entire future organism), each cell and each organ of the body can be classified according to these germ layers. Cells or organs that evolve from the inner germination layer (endoderm) will have the "relay" (command center) in the brain stem, the oldest brain structure.
In the middle germination layer, mesoderm, two groups are distinguished, one "older" and one "newer". Cells and organs that evolved from the "old" mesoderm have the relay in the cerebellum, belonging to the archaic brain, and those that evolved from the "new" mesoderm have the command relay in the brain marrow (the white substance of the brain). Cells and organs that have evolved from the outer germination layer (ectoderm) have the relay in the cerebral cortex (brain bark) that represents the newest (young) formation of our brain.
The first "moment" we can discuss stem cells has just been described. At the moment there are no cells that will become anything specific but, just cell layers composed of non-specialized cells, also called layers of stem cells. Moreover, these stem cells appear permanently, throughout the development range of the human embryo, because they are non-specialized cells that multiply, of course, through cell division and that permanently build the human embryo until the final phase of the fetus and child. As evidence in this permanent "construction" of the human embryo stem lies the way of sampling these stem cells.
They are taken, for example, from the umbilical cord (from here two types of stem cells are harvested: hematopoietic stem cells, harvested from umbilical cord blood and mesenchymal stem cells, harvested from the umbilical cord wall, i.e. from Wharton gelatin), the time of collection (the smaller the embryo, the better) being able to "stretch" throughout the pregnancy period and after (with reference to the actual time of birth). And, while i.e. this time of harvest, stem cells taken in the youngest stages of the embryo (fetus), also called embryonic stem cells, can give rise to any type of cell/tissue (which is why they are called "omnipotent") and are obtained from embryonic tissue (their use is "struck" by the ethical considerations of the medical world, and not only), and adult stem cells (which are harvested in the advanced stages of foetal development) have a slightly more limited ability to differentiate (being called pluripotent or multipotent) and can give rise to cells that can form different tissues (hepatic tissue, blood cells, nervous tissue, bone tissue, muscle, etc.). In current medical "technologies", these stem cells are used in regenerative medicine (but also in the treatment of a large number of conditions).
It would be good if I could give some details about how these stem cells are harvested. Invasive methods I do not want to discuss here because they refer either to an invasive sampling of the embryo itself (which is done either in violation of human, medical, etc. ethics with the slaughter, in most cases of the embryo, or with the justification of the non-viability of the pregnancy or the "necessary abortion" which entails, of course, the "justified" slaughter of the embryo). Well, that's not good, but it's practiced!!! The only non-invasive method of stem cell collection is achieved by means of blood remaining in the umbilical cord (this is a variable volume of blood that remains on the umbilical cord path to the placenta and inside the placenta itself which is richly vascularized) at the time of birth (without forgetting the Wharton gelatin present in both the umbilical cord and the placenta).
And now it's... These stem cells are "preserved" by various methods and then, at the appropriate time, given various "assignments". It comes "now it is now"... Experiments with embryonic stem cells (omnipotent) have confirmed that the placement of these cells in a certain environment "induces" the development of cells, for example, the liver. If the environment in which these cells are introduced changes, they will "produce" muscle cells. Another environment determines the development of nerve cells... And so on, it can "induce" the development of any type of cell. So, remember, it's the environment that determines what the omnipotent stem cells will become. In the case of other stem cells (pluripotents)... Hmmm, things are getting complicated.
For stem cells taken from embryos slaughtered by abortion or other "incidents" of similar value, the embryonic "origin" of the tissue from which they were taken becomes important, with adult stem cells already having "taken" information about the environment on which they will "dedicate" their existence. And thus, they will develop only certain groups of cells that "can" be "initiated" from their embryonic origin. More specifically, the environment will only attract a change of specialization in their development without reaching the stage of omnipotence.
And if you've got a hold of these stem cells non-invasively, there's a problem with the origin of those cells. The cord or placenta blood obviously belongs to the mother and not to the fetus. Or, by extension, it's a common blood. Without wanting to come to the conclusions of several researchers that we humans (actually any body-type life form) constantly generate stem cells that specialize immediately after the moment of their "creation", depending on the environment (as we have "seen" previously, the environment is the main determinant of the result of the "transformation" of the stem cell) and, in certain circumstances, according to the origin of the original embryonic "layer" of that cell.
Therefore, continuing the "logical presentation" of the cell groups, it is obvious that we conclude that the regeneration processes are not carried out simply by dividing a cell into two cells, one of which will take the place of the cell that has disappeared but, in fact, it is an "initial genetic manifestation" in which a cell divides according to its "genetic base" forming an adult stem cell which, "sensing" the environment in which it is located, will become "what it needs to be Interesting or not?!?
I'll continue in future posts!
Days
full of Love, Gratitude and Understanding!!!
Dorin, Merticaru