STUDY - Technical - New Dacian's Medicine
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Pages New Dacian's MedicineThe Life (Part 3) - About Life

Translation Draft

Let's talk now about adaptation and its mechanisms, continuing the general evolutionary line of study!

What could be the basis for adaptation, in terms of life (and implicitly of the human body)? And, why not, what is the point of this adaptation?!? Or secondary questions, "taken" from these "initial" questions...

The explanatory dictionary tells us that adaptation is the capacity, the process of reaction of living organisms (life forms) to the environment, resulting in a morphological change (a correlation of morphological structure) and physiological functions in relation to this environment...

The first step of our analysis will try to determine what it is and how adaptation manifests itself at the level of the cell (which we discussed so much and tiring in previous posts)... And, the starting point will be who decides this: RNA, DNA or the need to react to the environment (not to say directly "to something")..

At present it is almost generally accepted that it is genetic determinism that controls our adaptation (so there will be discussions about DNA and RNA). Genes are the ones that "attract" the "basal" development and functioning of our body... But now comes the first question mark...

Functionally, the RNA controls, structures, restores, etc. any form of protein from the cellular level and, by implication, to the body level...

DNA is just a form of additional control based on already "archived" information and... Very much... Partial destruction of DNA does not cause the cell to cease its activity but to continue it without problems (as long as the damage does not affect massive DNA "warehouses"), most often until its death (or "division with or without success", depending on the damaged DNA portion and the RNA's ability to restore the damaged structure)...

More strangely, the elimination of the entire nucleus, thus of all the DNA content (through and from chromosomes) to which the driving/determining functions of our life are assigned (I made this statement because there is still mitochondrial DNA) has the same result: the cell continues its activity most of the time until its "relatively natural" death (which can occur after 2 to 3 months)...

Yes, you read it right! If the nucleus containing most of the cellular DNA is extracted, the cell continues to live... Mitochondrial DNA, existing in the dozens of organelles (referring to mitochondria) even if it is more unstable, by genetic errors leads to the "fall" of that organelle and has almost no effect on the cell, its "stability" given precisely by this effect of "insensitivity to disorders", compatible with a kind of "stability"...

And so, we've reached the point where we can make a totalization of the effects related to DNA damage and its effects on cell function and, by implication, an organism... DNA plays a "main" role at the time of cell reproduction...

So for an organism has a massive role at the time of its formation (of procreation, then of division, then intraovulatory or intrauterine growth - here, in fact, I mean only the animal cell, the body and certain characteristics of it such as the color of the eyes, hair, etc.).

Possibly it also plays a role in the reconstitution of the organism, in the processes of "replacement" of dead cells or "replacement"... But this is where the "stem" processes that we have discussed and will discuss.

As for the later part, after the "completion" of the cell growth (or division), DNA has only the role of "matrix" for processes directly related to the synthesis, processing, etc. of proteins or other substances that are carried out by RNA...

To understand why geneticists use this term, "matrix," I'll make a little parenthesis... An RNA (no longer complicating you with technical descriptions) wants to replicate, or is asked to... Ok... He will "circulate" to DNA and can only "couple" with the area of DNA that allows this coupling... From that moment begins a replication process according to the "model" present in the respective structure of DNA...

The result will obviously be a future RNA, but not an RNA... That's because "replication" has not led to the formation of RNA itself but to some kind of basis of its creation, using the possible usable way of transmitting information from the DNA level...

It sounds complicated, but it's not like that. The elements of chemical interaction (valences, blah, blah) will "request" the "product" of this replication a kind of folding from a kind of polymer filament to the bicatenary form of the RNA in question (described in the previous post, RRNA).

So, if the DNA is "destroyed" this sequence of "replication", RRNA (if we considered it an example), in the first place it will not be able to "coupling" to initiate the replication process.

And even if he "succeeds" this, what about the chemical synchronisms at the time of "bending" for the formation of the bicatenary structure?!? Obviously it will be impossible. Or it will be possible as we talk about a body that "provides" a form of functionality, a kind of "balance" presence, which can be considered to be a new element with a new functionality...

So, if the "final product" of phenomena, processes described above is viable, it is clear that we are discussing the processes of evolution that arise directly from this... And, this product, it can be "rectified" by the environment or genetic restoration processes that I will discuss in future posts.

Well, now I'm going to get into a little medical detail. From what we described can we raise the question of how to get to "DNA degradation" with the unpleasant effects of cancer?

The vast majority of our body's cells recover periodically (as we have presented in previous posts or rows). For a few reasons (which we will discuss in the posts to come) it comes to the "defect" of this mold (from the DNA).

Thus, the other components of the "genotypic chain" remain without the mold "construction", "control" or whatever you want to think and then the defect is propagated with effects that can give some character of influence of life (literally) that can go up to the death of the cell, to the cancer cell or others...

But this DNA degradation alone is not enough, requiring the accumulation of some kind of "critical mass" of such "degraded" cells, helpful elements and much more (see previous and future posts).

So, also as part of our effort to draw a conclusion on the gene influence, it is good to remember (from previous posts) that the cancer cell (literally) must be "supported" by the development of other "helping" structures and even without regard to it, the cancer cell, literally, has no "effect" on its own, requiring a certain mass of cells (a certain number), not attacked by the body's defense mechanisms, and a duration of "activity supported by the body" in order to reach this critical mass... Not to mention that the phenomena of metastasis are also related to completely different circumstances than genotype...

And so we have come to "activity supported by the body itself" or, as a way out for classical doctors, a "chaotic cellular development activity of the neoformation type" supported by the body itself by "not recognizing" that structure in the sense of initiated elimination processes.

So the "genetic limit" of the approach to cancer "falls", literally, possibly can be speculated within the known genetic degradation limit are the genetic name of "genetic defects".

In this case, if we consider the "mass" of people who may be affected by "genotype activities" in which we will take into account individuals with genetic diseases and those who "manifest" their genotype in other diseases, we will reach a total share of up to 5 - 6% of the population...

So it can be said, after all this, that the genotype, what "is the basis of our life, of our identity" within a limit hard to consider small (without "reminding us" of the phases of procreation and possibly cellular restorations throughout life - you will see, in future posts, that this cellular recovery with all its implications, is related to other things altogether)... Maximum 5 – 6% of cases at the level of humanity, as a population.

In order to understand where I "got" (in fact, where the medical world came from these figures) the total weight of 5 - 6% is necessary to make the following clarifications...

Genetic diseases, diseases or genetic predispositions are directly related to these genes (which is why they are referred to as "genetic disorders")... But in this case, the "affected" share of the population is very small (a maximum of 5% is circulated in medical statistics... So the actual "genetic capacity for damage" is pretty low.

And these genetic diseases, most of the time, are unrelenting because they manifest themselves in a body "against nature" (a body that is built, from the start, wrong), the genetic condition being a defect easily comparable to a defect "from the start" therefore, not to be taken into account in a correct statistic about influence.

Even with genetic predispositions, things have a completely different approach (which we will eventually discuss later)... But essentially even these "genetic disorders" are related to the considerations and especially the beliefs of the affected person (for example there are many cases of individuals affected by Down syndrome who can end up completing high school; in Romania I remember the case of Mihai Moceanu from Cluj) and, unfortunately, and the beliefs of those around him, of society, the case of a student at the University of Sheffield with hydrocephalus - "water to the brain" - who finishes a college and is completely normal from a social point of view but he actually had no brain, his skull being mainly filled with cerebrospinal fluid, scanning the "brain" revealing that between the ventricles and the cortical surface there was only a thin layer of membrane with a thickness of one millimeter , etc.).

So, DNA is, as we've discovered several times so far, just a storage medium.

As for RNA, it is not good to "walk" because it intervenes "independently of DNA" in protein synthesis, in cellular breathing processes, in "transit", transport processes, etc. and the cell often dies almost immediately. But RNA has no "gene" connection to cell division, so... What can we put behind the RNA in terms of genotype???

But if we come to consider the "reactions" to the environment, we will see that RNA has a decisive role even in DNA repair (even in "filling" it), at certain "points" in its restoration and, more importantly, it intervenes in protein synthesis (or other vital materials... which we will discuss tomorrow...) of the cell... So, at least here, the considerations of genotypic manifestation are beginning to demand our attention...

Moreover, from what you will go through in future posts you will find that DNA is often completed, even rewritten under certain conditions of persistence of environmental factors, even under conditions of "coordinated perceptions" voluntarily controlled by the owner of those genes.

So everything that happens in the cell, and therefore also in the body, is a direct consequence of the cell's need for protein or other substances, including to accumulate with possible chances of genetic transmission, in a new individual these accumulations...

But, factually, in terms of the survival needs of the cell, it actually comes down to what enters the cell and is processed according to its needs and, of course, what comes out of the cell (also in correlation with cellular needs...).

That's where the membrane comes in with its selective permeability... So the RNA also loses its great command center role that was originally assigned to DNA.... It's all about selective permeability now... And, as we present in previous posts, the membrane is able to make the selection of what enters or leaves the cell based on simple feedback mechanisms (automatic response to something determined such as protein, amino acid, hormone, genetic fragment, "sweet materials", "fat materials" and so on) ...

And, in addition, this "response" has the "gift" to ask the membrane for supplementation or reduction of the mechanisms that achieve all this, depending on the environment (in response to environmental demands, as long as they do not affect cellular viability, implicitly supplemented by membrane viability)...

What if you expand this reasoning by considering considerations such as: "Fear or the threat of imminent danger causes the secretion of adrenaline... If the level of these perceptions, not to say directly feelings or emotions, causes constant or increasingly increased "evacuations" of adrenaline, everything will, over time, increase the number of constituent elements of the mechanism of synthesis and adrenaltransfer at the level of the cell...

This increase (strengthening) of the adrenalitic mechanism will be transmitted to the newly produced cell (with the role of replacing the one that has ended its life cycle) and thus we are dealing with a cell more prepared to the environmental factors "penalized" with increased adrenal secretion...

And so, over time, where a related reaction to adrenaline is required, we'll have cells with increased adrenalitic "transit"... Does this have anything to do with the genotype???

In a way, yes... Because in certain replicative areas of DNA there will be an inscription of the need for "adrenaline reaction", the density of the producing elements, the density of the membranary "gates", etc., the new cells being thus better prepared to cope with the environment...

But not as a manifestation of DNA, possibly the nucleus of the command center cell... It's all just a feedback determinism and not a manifestation of a command center... A reaction of an ensemble, with elements that have well delineated their symbiotic role and, by no means particular.

And remember, we are not discussing chemical, vital, cell (organism) demands and discussing the influence of some perceptions, possibly of feelings, of certain beliefs (fear can also be born of imagination, not only of a real, palpable danger)... So here's the first link between feelings, emotions and the "evolutionary" restructuring of DNA (possibly other structures).

As a small analogy, I'd better present to you something particularly interesting... If it is the cell membrane that senses the outside world and "dictates" the selective behavior of the cell, it can be said that the skin becomes very similar to a brain (a driving element)...

The previous analogy that says that what is found in the cell is found and in the human body now has a connotation... Between the human brain and human skin (cell membrane homologous, at least as a position) there is a common "embryo" starting point...

In embryology there are three "initial" embryonic layers (layers of cells, each layer giving rise to different organs and tissues), which create the completely final body: ectoderm, mesoderm and endoderm. The outer layer, the ectoderm, gives rise to only two "things" in the human body: the skin and the brain with the nervous system... Moving on... We'll see you in future posts!

So, the determinism of feedback, "response", is the one in which we are not controlled by genes but we are controlled by the environment, possibly by perceptions "from" it (in fact, only in humans, where the processing and conscious selection of perceptions, by our beliefs...) realized towards the manifestation of the external environment.

And this is about the great mass of humans (the mass of 94 - 95% left considered as being without "genetic problems" - even if their bodies with disabilities conform to the determinism of feedback, as he can) who, without having "genetic problems" do all kinds of diseases, including cancer (which starts with damage/ genetic modification)...

To recall those presented to the world of souls, their possible definite influence, intervention that "departs" from the genetic material "initial" and can occur to the genetic material "final", transmissible to a new human being?!?

But that's enough for today! And tomorrow will be a good day...

First day of the weekend... Have fun!!!

Dorin, Merticaru